Mary&May Spicule Azelaic PDRN Spot Cream is a moisturizer with 69 ingredients. It is rated "use caution" in pregnancy because it contains Salicylic Acid. Common allergens: fragrance, essential oils, niacinamide.
Sensitive skin: fragrance, essential oils, niacinamide Why?
- fragrance: Fragrance or parfum, and scent ingredients listed by name, such as linalool and limonene. The most common cause of skincare allergies; worth avoiding if you have eczema, rosacea, or very sensitive skin.
- essential oils: Plant oils such as tea tree, lavender, citrus peel, and peppermint. Natural, but a common cause of irritation and allergies, especially on sensitive or broken skin.
- niacinamide: A popular, well-tolerated ingredient that can cause redness or flushing for a few people, especially at high strengths.
These flags don't affect the pregnancy rating. They point out the ingredients most likely to make skincare sting, itch, or cause a rash. If your skin is sensitive, or one of them has bothered you before, you may want to skip the product or patch-test it first. Most people use them without a problem.
How we flag ingredientsWhat does it do?
A moisturizer keeps skin hydrated and soft.
Based on its ingredients, it's made to:
Helps with pimples and clogged pores
Ingredients used to clear breakouts and keep pores from clogging.
From Melaleuca Alternifolia (Tea Tree) Leaf Water (no. 2), Azelaic Acid (no. 27), Salicylic Acid (no. 45), Melaleuca Alternifolia (Tea Tree) Leaf Oil (no. 56)
Exfoliates
Loosens dead skin cells so skin looks smoother and brighter. Use it a few times a week, not every day, if your skin is sensitive.
From Salicylic Acid (no. 45)
Evens out skin tone
Used to fade dark spots and marks and even out skin tone over time.
From Niacinamide (no. 23), Azelaic Acid (no. 27)
Hydrates
Draws water into the skin, so it feels plumper and less tight.
From Sodium Hyaluronate (no. 13), Polyglutamic Acid (no. 14)
Supports the skin barrier
Helps skin hold on to moisture and protect itself, which matters most for dry or irritated skin.
From Cholesterol (no. 9), Ceramide NP (no. 15)
Worked out from the ingredient list. Labels don't show amounts, so how well it works depends on the formula and your skin.
Is Mary&May Spicule Azelaic PDRN Spot Cream safe to use during pregnancy?
Jouaxia rates Mary&May Spicule Azelaic PDRN Spot Cream "Use caution" for pregnancy because it contains Salicylic Acid. Salicylic acid / BHA: ACOG says over-the-counter salicylic acid products may be used if needed, but absorption rises with frequent use or large areas; avoid high-strength peels (MotherToBaby/ACOG, Bozzo et al. 2011). This is general information, not medical advice. Check with your OB-GYN or dermatologist.
Does Mary&May Spicule Azelaic PDRN Spot Cream contain fragrance or other common allergens?
Yes. Mary&May Spicule Azelaic PDRN Spot Cream contains fragrance, essential oils, niacinamide, which can bother sensitive skin. This doesn't affect its pregnancy rating, and most people use these ingredients without a problem; if your skin is sensitive or you've reacted to one before, patch-test it first or look for an alternative.
Is it OK for kids and teens?
Kids (ages 3–11)
Use with care
- Acne treatment (Salicylic Acid): Benzoyl peroxide, salicylic acid, and adapalene treat acne well, but for children under 12 it's best to check with a doctor first, and to start gently.
- Fragrance or essential oils (Melaleuca Alternifolia (Tea Tree) Leaf Oil, Limonene): Children's skin reacts to fragrance and essential oils more easily; fragrance-free products are the usual advice for kids, especially with eczema or sensitive skin.
Teens (ages 12–17)
Use with care
- Essential oils (Melaleuca Alternifolia (Tea Tree) Leaf Oil): A known cause of allergic skin reactions, such as to lavender and tea tree oils.
Helps with acne: Niacinamide, Azelaic Acid, Salicylic Acid.
General guidance from the ingredient list, not medical advice. For babies under 3, or skin problems that don't get better, ask a doctor. How we rate for kids and teens · Skincare for teens
What are the ingredients in Mary&May Spicule Azelaic PDRN Spot Cream?
69 ingredients. The ones we flag come first, with their place on the label. Select an ingredient to see what it does.
Salicylic Acid no. 45 on the label
Use caution in pregnancy: Salicylic acid / BHA. ACOG says over-the-counter salicylic acid products may be used if needed, but absorption rises with frequent use or large areas; avoid high-strength peels (MotherToBaby/ACOG, Bozzo et al. 2011).
Niacinamide no. 23 on the label
Sensitive skin: niacinamide.
Melaleuca Alternifolia (Tea Tree) Leaf Oil no. 56 on the label
Sensitive skin: essential oils.
Limonene no. 57 on the label
Sensitive skin: fragrance.
65 other ingredients: nothing flaggedShow
- 1.Water
- 2.Melaleuca Alternifolia (Tea Tree) Leaf Water
- 3.1,2-Hexanediol
- 4.Ethylhexylglycerin
- 5.Propylene Glycol
- 6.Brassica Campestris (Rapeseed) Sterols
- 7.Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate
- 8.Polyglyceryl-10 Laurate
- 9.Cholesterol
- 10.Hydrogenated Lecithin
- 11.Glycerin
- 12.Disodium EDTA
- 13.Sodium Hyaluronate
- 14.Polyglutamic Acid
- 15.Ceramide NP
- 16.Stearic Acid
- 17.Tocopherol
- 18.Oleic Acid
- 19.Cetyl Ethylhexanoate
- 20.Vinyl Dimethicone
- 21.Macadamia Ternifolia Seed Oil
- 22.Butyrospermum Parkii (Shea) Butter
- 24.Dipropylene Glycol
- 25.Hydroxyacetophenone
- 26.Caprylyl Glycol
- 27.Azelaic Acid
- 28.Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
- 29.Polyisobutene
- 30.Caprylyl/Capryl Glucoside
- 31.Sorbitan Oleate
- 32.Ammonium Acryloyldimethyltaurate/VP Copolymer
- 33.Glyceryl Acrylate/Acrylic Acid Copolymer
- 34.Pvm/MA Copolymer
- 35.Polypropylsilsesquioxane
- 36.Methylpropanediol
- 37.Panthenol
- 38.C14-22 Alcohols
- 39.C12-20 Alkyl Glucoside
- 40.Caprylic/Capric Triglyceride
- 41.Sodium Hydroxide
- 42.Acrylates/C10-30 Alkyl Acrylate Crosspolymer
- 43.Glyceryl Stearate
- 44.Tromethamine
- 46.Hydrolyzed Sponge
- 47.Zinc PCA
- 48.Erythritol
- 49.Helianthus Annuus (Sunflower) Seed Oil
- 50.Copper Chlorophyll
- 51.Rosmarinus Officinalis (Rosemary) Extract
- 52.Lauryl Glucoside
- 53.Myristyl Glucoside
- 54.Polyglyceryl-6 Laurate
- 55.Allantoin
- 58.Alpha-Terpinene
- 59.Hexamethylindanopyran
- 60.Pinene
- 61.Terpineol
- 62.Terpinolene
- 63.Xanthan Gum
- 64.Butylene Glycol
- 65.Centella Asiatica Extract
- 66.Sodium DNA
- 67.Magnolol
- 68.Honokiol
- 69.Madecassoside
Ingredient list from YesStyle. Formulas change, so check the packaging of the product you buy.